SCHEMBL28304501

SCHEMBL28304501

CC1CCc2cc3c(cc2C1)CCCC3

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 2/20 0.37
DRD1 P21728 1/20 0.37
ALDH1A1 P00352 7/20 0.36
MAPT P10636 4/20 0.36
NFKB1 P19838 1/20 0.36
THPO P40225 1/20 0.36
HIF1A Q16665 1/20 0.36
HSD17B10 Q99714 1/20 0.36
USP2 O75604 1/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
KDM4E B2RXH2 3/20 0.35
CYP2A6 P11509 2/20 0.33
CYP2A13 Q16696 1/20 0.33
TSHR P16473 1/20 0.33
FYN P06241 1/20 0.33
CDC25B P30305 1/20 0.32
MEN1 O00255 2/20 0.32
PKM P14618 2/20 0.32
KMT2A Q03164 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12305071 0.80 MAPT (0.59) DRD2DRD1ALDH1A1MAPTNFKB1
SCHEMBL14525559 0.80 DRD2 (0.36) DRD2DRD1ALDH1A1MAPTNFKB1
SCHEMBL26178860 0.80 SIGMAR1 (0.42) DRD2DRD1ALDH1A1MAPTNFKB1
SCHEMBL15413018 0.78 ATM (0.41) DRD2DRD1ALDH1A1MAPTNFKB1
SCHEMBL12924515 0.77 CYP3A4 (0.46) DRD2DRD1ALDH1A1MAPTKDM4E
SCHEMBL15413015 0.77 DRD2 (0.32) DRD2DRD1ALDH1A1MAPTNFKB1
SCHEMBL25945156 0.75 CYP2A6 (0.34) ALDH1A1MAPTNPC1CYP2A6CYP2A13
SCHEMBL13218790 0.74 ALDH1A1 (0.36) DRD2DRD1ALDH1A1MAPTNFKB1
SCHEMBL8912019 0.74 AHR (0.38) DRD2ALDH1A1NPC1RAB9AKDM4E
SCHEMBL14525561 0.72 HTR2A (0.44) DRD2DRD1ALDH1A1MAPTNFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107235818-B Method based on cobalt salt selective catalytic hydrogenation polycyclic aromatic hydrocarbon 四川大学 2019-07-09 CN disclosed