Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.43 |
| ▸ | F3 | P13726 | 1/20 | 0.43 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL810373 | 0.81 | LMNA (0.55) | ALDH1A1LMNAKMT2AHTTTDP1 | |
| SCHEMBL4169756 | 0.76 | ALDH1A1 (0.65) | ALDH1A1LMNAKMT2ATDP1CYP2C9 | |
| SCHEMBL25288322 | 0.75 | ALDH1A1 (0.59) | ALDH1A1LMNAKMT2ATDP1CYP2C9 | |
| SCHEMBL2491556 | 0.74 | ALDH1A1 (0.71) | ALDH1A1LMNAKMT2ATDP1CYP2C9 | |
| SCHEMBL31648307 | 0.74 | ALDH1A1 (0.71) | ALDH1A1LMNAKMT2ATDP1CYP2C9 | |
| SCHEMBL30659698 | 0.74 | ALDH1A1 (0.71) | ALDH1A1LMNAKMT2ATDP1CYP2C9 | |
| SCHEMBL30605728 | 0.74 | ALDH1A1 (0.62) | ALDH1A1LMNAKMT2ATDP1PLOD2 | |
| SCHEMBL27851778 | 0.74 | ALDH1A1 (0.62) | ALDH1A1LMNAKMT2ATDP1APP | |
| SCHEMBL28103782 | 0.74 | ALDH1A1 (0.62) | ALDH1A1LMNAKMT2ATDP1PLOD2 | |
| SCHEMBL1173304 | 0.73 | ALDH1A1 (0.53) | ALDH1A1LMNAKMT2ATDP1PLOD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105764514-B | Aminopyridine derivatives as inhibitors of TAM family kinases | 圣诺康生命科学公司 | 2019-07-12 | — | — | CN | disclosed |