Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ECE1 | P42892 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nicotinic Acid Hydrazide SCHEMBL29648965 | 0.86 | HDAC1 (0.69) | KMT2AKDM4ERAB9AMEN1NPC1 | |
| Nicotinic Acid Hydrazide SCHEMBL258390 | 0.86 | HDAC1 (0.69) | KMT2AKDM4ERAB9AMEN1NPC1 | |
| Nicotinic Acid Hydrazide SCHEMBL28127107 | 0.84 | HDAC1 (0.62) | KMT2AKDM4ERAB9AMEN1NPC1 | |
| Nicotinic Acid Hydrazide SCHEMBL31491467 | 0.84 | HDAC1 (0.67) | KMT2AKDM4ERAB9AMEN1NPC1 | |
| Nicotinic Acid Hydrazide SCHEMBL28747918 | 0.84 | HDAC1 (0.67) | KMT2AKDM4ERAB9AMEN1NPC1 | |
| Benzoic Acid Hydrazide SCHEMBL5778873 | 0.81 | GAA (0.70) | KMT2AKDM4ERAB9AMEN1NPC1 | |
| Nicotinic Acid Hydrazide SCHEMBL28112815 | 0.78 | HDAC1 (0.59) | KMT2AKDM4ERAB9AMEN1NPC1 | |
| SCHEMBL360711 | 0.78 | PLOD2 (0.69) | NAPRTKMT2AKDM4ERAB9AMEN1 | |
| SCHEMBL29430342 | 0.77 | NAPRT (1.00) | NAPRTKDM4EEPHX2CYP2C9CYP1A2 | |
| SCHEMBL48609 | 0.77 | NAPRT (1.00) | NAPRTKDM4EEPHX2CYP2C9CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105764514-B | Aminopyridine derivatives as inhibitors of TAM family kinases | 圣诺康生命科学公司 | 2019-07-12 | — | — | CN | disclosed |