Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.69 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.69 |
| ▸ | THRB | P10828 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | F7 | P08709 | 1/20 | 0.62 |
| ▸ | F3 | P13726 | 1/20 | 0.62 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.62 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.62 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.62 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.62 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.62 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.62 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.62 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.61 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.61 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nicotinic Acid Hydrazide SCHEMBL29648965 | 1.00 | HDAC1 (0.69) | HDAC1HDAC6THRBLMNAHIF1A | |
| Nicotinic Acid Hydrazide SCHEMBL28747918 | 0.98 | HDAC1 (0.67) | HDAC1HDAC6THRBLMNAHIF1A | |
| Nicotinic Acid Hydrazide SCHEMBL31491467 | 0.98 | HDAC1 (0.67) | HDAC1HDAC6THRBLMNAHIF1A | |
| Nicotinic Acid Hydrazide SCHEMBL28127107 | 0.94 | HDAC1 (0.62) | HDAC1HDAC6THRBLMNAHIF1A | |
| Nicotinic Acid Hydrazide SCHEMBL28112815 | 0.91 | HDAC1 (0.59) | HDAC1HDAC6THRBLMNAHIF1A | |
| Benzoic Acid Hydrazide SCHEMBL5778873 | 0.88 | GAA (0.70) | HDAC1HDAC6THRBF7F3 | |
| SCHEMBL2833544 | 0.87 | ROCK2 (0.69) | HDAC1HDAC6LMNAHIF1AROCK2 | |
| Nicotinic Acid Hydrazide SCHEMBL28304573 | 0.86 | NAPRT (0.61) | HDAC1HDAC6THRBLMNAPLOD2 | |
| SCHEMBL1019295 | 0.85 | HDAC1 (0.65) | HDAC1HDAC6THRBLMNAHIF1A | |
| Nicotinic Acid Hydrazide SCHEMBL28304575 | 0.84 | HCAR2 (0.57) | HDAC1HDAC6THRBLMNAHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 997 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122080895-A | Polyglycolic acid composition and preparation method thereof, biodegradable polyester material and application thereof, and PGA temporary plugging ball and preparation method thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-119391251-B | Super-hydrophobic anti-icing coating for power transmission line and preparation method thereof | 和通数联(北京)科技工程有限公司 | 2025-04-18 | — | — | CN | claimed |
| CN-118994321-B | Preparation method and application of cosmetic cyclic peptide reagent | 杭州皓阳生物技术有限公司 | 2025-02-14 | — | — | CN | claimed |
| US-20250051805-A1 | METHODS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2025-02-13 | — | — | US | claimed |
| CN-119391251-A | Super-hydrophobic anti-icing coating for power transmission line and preparation method thereof | 和通数联(北京)科技工程有限公司 | 2025-02-07 | — | — | CN | claimed |
| CN-118994321-A | Preparation method and application of cosmetic cyclic peptide reagent | 杭州皓阳生物技术有限公司 | 2024-11-22 | — | — | CN | claimed |
| CN-118638274-A | Polyvinyl alcohol microsphere and preparation method and application thereof | 湖南埃普特医疗器械有限公司 | 2024-09-13 | — | — | CN | claimed |
| US-12071503-B2 | Method for preparing and repairing covalent organic framework materials | ZHEJIANG UNIVERSITY (CN) | 2024-08-27 | — | — | US | claimed |
| CN-118359536-A | Novel-structure compound and application thereof in aspect of cryopreservation protection of stem cells | 南京泓纬医药科技有限公司 | 2024-07-19 | — | — | CN | claimed |
| US-20240239765-A1 | GLYCINE N-METHYLTRANSFERASE SPECIFIC ENHANCER AND PREPARATION METHOD AND USES THEREOF | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2024-07-18 | — | — | US | claimed |
| EP-1392219-A4 | SUBSTITUTED N'-(ARYLCARBONYL)-BENZHYDRAZIDES, N'-(ARYLCARBONYL)-BENZYLIDENE-HYDRAZIDES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOTOSIS AND THE USE THEREOF | CYTOVIA INC (US) | 2007-01-24 | — | — | EP | claimed |
| US-20040186078-A1 | Substituted N'-(arylcarbonyl)-benzhydrazides, N'-(arylcarbonyl)-benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof | CYTOVIA, INC. | 2004-09-23 | — | — | US | claimed |
| EP-1392219-A2 | SUBSTITUTED N'-(ARYLCARBONYL)-BENZHYDRAZIDES, N'-(ARYLCARBONYL)-BENZYLIDENE-HYDRAZIDES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOTOSIS AND THE USE THEREOF | Cytovia, Inc. (US) | 2004-03-03 | — | — | EP | claimed |
| US-20030013743-A1 | Substituted N'-(arylcarbonyl)-benzhydrazides, N'-(arylcarbonyl)-benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof | CYTOVIA, INC. | 2003-01-16 | — | — | US | claimed |
| WO-2002089745-A2 | SUBSTITUTED N'-(ARYLCARBONYL)-BENZHYDRAZIDES, N'-(ARYLCARBONYL)-BENZYLIDENE-HYDRAZIDES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF | CYTOVIA, INC. (US) | 2002-11-14 | — | — | WO | claimed |
| EP-0322691-B1 | Process for producing 1-acyl-2-pyrazoline derivatives | MITSUI TOATSU CHEMICALS (JP) | 1994-06-15 | — | — | EP | claimed |
| US-4956301-A | Test for diagnosis of diabetes, pads with indicators sensitive to fructosamine | MILES INC. (US) | 1990-09-11 | — | — | US | claimed |
| EP-0274928-A2 | Use of xanthine-oxydase inhibitors in the manufacture of a pharmaceutical composition for the treatment of glaucoma, and pharmaceutical compositions for the treatment of glaucoma | LABORATOIRES CHAUVIN (FR) | 1988-07-20 | — | — | EP | claimed |
| EP-0214158-A1 | ANTHELMINTIC PYRIDINYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1987-03-18 | — | — | EP | claimed |
| WO-1986004582-A1 | ANTHELMINTIC PYRIDINYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1986-08-14 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040186078-A1 | Substituted N'-(arylcarbonyl)-benzhydrazides, N'-(arylcarbonyl)-benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof | CASP2, CASP1, BCL2 | HDAC1 34/4885HDAC6 102/4885THRB 2238/4885 |
| US-20240239765-A1 | GLYCINE N-METHYLTRANSFERASE SPECIFIC ENHANCER AND PREPARATION METHOD AND USES THEREOF | GNMT, NNMT, HNMT | HDAC1 733/4885HDAC6 2260/4885THRB 1935/4885 |
| US-20250051805-A1 | METHODS | BRDT, BRPF3, BRD4 | HDAC1 422/4885HDAC6 719/4885THRB 2974/4885 |
| US-20030013743-A1 | Substituted N'-(arylcarbonyl)-benzhydrazides, N'-(arylcarbonyl)-benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof | CASP2, CASP1, BCL2 | HDAC1 34/4885HDAC6 102/4885THRB 2238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.