Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.69 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.69 |
| ▸ | THRB | P10828 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | F7 | P08709 | 1/20 | 0.62 |
| ▸ | F3 | P13726 | 1/20 | 0.62 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.62 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.62 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.62 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.62 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.62 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.62 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.62 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.61 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.61 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nicotinic Acid Hydrazide SCHEMBL258390 | 1.00 | HDAC1 (0.69) | HDAC1HDAC6THRBLMNAHIF1A | |
| Nicotinic Acid Hydrazide SCHEMBL28747918 | 0.98 | HDAC1 (0.67) | HDAC1HDAC6THRBLMNAHIF1A | |
| Nicotinic Acid Hydrazide SCHEMBL31491467 | 0.98 | HDAC1 (0.67) | HDAC1HDAC6THRBLMNAHIF1A | |
| Nicotinic Acid Hydrazide SCHEMBL28127107 | 0.94 | HDAC1 (0.62) | HDAC1HDAC6THRBLMNAHIF1A | |
| Nicotinic Acid Hydrazide SCHEMBL28112815 | 0.91 | HDAC1 (0.59) | HDAC1HDAC6THRBLMNAHIF1A | |
| Benzoic Acid Hydrazide SCHEMBL5778873 | 0.88 | GAA (0.70) | HDAC1HDAC6THRBF7F3 | |
| SCHEMBL2833544 | 0.87 | ROCK2 (0.69) | HDAC1HDAC6LMNAHIF1AROCK2 | |
| Nicotinic Acid Hydrazide SCHEMBL28304573 | 0.86 | NAPRT (0.61) | HDAC1HDAC6THRBLMNAPLOD2 | |
| SCHEMBL1019295 | 0.85 | HDAC1 (0.65) | HDAC1HDAC6THRBLMNAHIF1A | |
| Nicotinic Acid Hydrazide SCHEMBL28304575 | 0.84 | HCAR2 (0.57) | HDAC1HDAC6THRBLMNAHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119874681-A | Indole derivative, preparation method thereof and application of indole derivative in resisting liver cancer | 中国人民解放军北部战区总医院 | 2025-04-25 | — | — | CN | claimed |
| EP-4673444-A1 | OXADIAZOLE DERIVATIVE COMPOUNDS, AND THE PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Chong Kun Dang Pharmaceutical Corp. (KR) | 2026-01-07 | — | — | EP | disclosed |
| CN-115850241-B | Substituted heterocyclic compound containing alpha-ketone skeleton and application thereof | 中国药科大学 | 2025-01-14 | — | — | CN | disclosed |
| WO-2024180464-A1 | OXADIAZOLE DERIVATIVE COMPOUNDS, AND THE PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2024-09-06 | — | — | WO | disclosed |
| CN-118464808-A | Method for detecting fluorine ions and application thereof | 华南师范大学 | 2024-08-09 | — | — | CN | disclosed |
| CN-114174292-B | Substituted 2-morpholinopyridine derivatives as ATR kinase inhibitors | 修复治疗公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-111527084-B | Isofuranone compounds useful as HPK1 inhibitors | 百时美施贵宝公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-115850241-A | Substituted heterocyclic compound containing alpha-ketone skeleton and application thereof | 中国药科大学 | 2023-03-28 | — | — | CN | disclosed |
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | disclosed |