Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | APP | P05067 | 1/20 | 0.55 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.55 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | F7 | P08709 | 1/20 | 0.49 |
| ▸ | F3 | P13726 | 1/20 | 0.49 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1479171 | 0.92 | NAPRT (0.53) | LMNAKMT2ATDP1PLOD2GAA | |
| Tibenzate SCHEMBL2110094 | 0.84 | IDO1 (0.52) | LMNAKMT2ATDP1SMN1; SMN2 | |
| SCHEMBL28460668 | 0.80 | IDO1 (0.52) | LMNAKMT2ATDP1 | |
| SCHEMBL27497158 | 0.76 | SMN1; SMN2 (0.54) | LMNAKMT2ATDP1PLOD2GAA | |
| SCHEMBL360711 | 0.76 | PLOD2 (0.69) | LMNAKMT2ATDP1PLOD2GAA | |
| SCHEMBL3247900 | 0.75 | GPR52 (0.61) | LMNAKMT2ATDP1PLOD2GAA | |
| Niacin SCHEMBL17633821 | 0.75 | ALDH1A1 (0.57) | LMNAKMT2ATDP1PLOD2GAA | |
| Bromide SCHEMBL11040809 | 0.75 | PLOD2 (0.67) | LMNAKMT2ATDP1PLOD2GAA | |
| Hydrochloric Acid SCHEMBL11169565 | 0.75 | PLOD2 (0.67) | LMNAKMT2ATDP1PLOD2GAA | |
| SCHEMBL11189149 | 0.74 | SMN1; SMN2 (0.74) | LMNAKMT2AGAAALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106928134-B | A kind of preparation facilities and synthetic method of nicosulfuron intermediate | 山东理工大学 | 2019-07-16 | — | — | CN | disclosed |