Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5390967 | 0.83 | ALDH1A1 (0.55) | ALDH1A1KMT2APOLBMAPTKDM4E | |
| SCHEMBL7403378 | 0.81 | RORC (0.47) | KMT2APOLBHDAC1HDAC3HDAC4 | |
| SCHEMBL8462115 | 0.81 | RORC (0.47) | KMT2APOLBHDAC1HDAC3HDAC4 | |
| SCHEMBL28124499 | 0.80 | ALDH1A1 (0.52) | ALDH1A1KMT2APOLBMAPTKDM4E | |
| SCHEMBL27480093 | 0.80 | ALDH1A1 (0.52) | ALDH1A1KMT2APOLBMAPTKDM4E | |
| SCHEMBL1695124 | 0.79 | ALDH1A1 (0.55) | ALDH1A1KMT2APOLBMAPTKDM4E | |
| SCHEMBL8484356 | 0.78 | KMT2A (0.56) | ALDH1A1KMT2APOLBMAPTKDM4E | |
| SCHEMBL11143477 | 0.77 | RAB9A (0.55) | ALDH1A1KMT2APOLBMAPTKDM4E | |
| SCHEMBL6291224 | 0.77 | RAB9A (0.49) | ALDH1A1KMT2APOLBMAPTGPR139 | |
| SCHEMBL27308671 | 0.77 | RAB9A (0.49) | ALDH1A1KMT2APOLBMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023302-A | 2,4, 5-trisubstituted 1,2, 4-triazolones as DHODH inhibitors | 拜耳股份有限公司 | 2019-07-16 | — | — | CN | claimed |