Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28305044 | 0.78 | MEN1 (0.42) | KDM4EMEN1NPC1MITFALDH1A1 | |
| Acetic Acid SCHEMBL28306107 | 0.77 | MEN1 (0.45) | KDM4EMEN1NPC1MITFALDH1A1 | |
| SCHEMBL11434731 | 0.74 | OPRM1 (0.50) | KDM4EMEN1NPC1MITFALDH1A1 | |
| SCHEMBL11434729 | 0.74 | OPRM1 (0.50) | KDM4EMEN1NPC1MITFALDH1A1 | |
| SCHEMBL11331790 | 0.71 | ALDH1A1 (0.47) | SLC18A3KDM4EMEN1NPC1MITF | |
| SCHEMBL27345981 | 0.71 | KDM4E (0.43) | KDM4EMEN1NPC1MITFALDH1A1 | |
| SCHEMBL3276186 | 0.71 | SLC18A3 (0.58) | SLC18A3KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL3276190 | 0.71 | SLC18A3 (0.58) | SLC18A3KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL8961737 | 0.71 | SLC18A3 (0.58) | SLC18A3KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL3276187 | 0.71 | SLC18A3 (0.58) | SLC18A3KDM4EMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110018540-A | Stretched film and its manufacturing method | 柯尼卡美能达株式会社 | 2019-07-16 | — | — | CN | disclosed |
| CN-110014679-A | The manufacturing method of stretched film | 柯尼卡美能达株式会社 | 2019-07-16 | — | — | CN | disclosed |