Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2B known ✓ | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C known ✓ | P18825 | 1/20 | 0.38 |
| ▸ | OPRK1 known ✓ | P41145 | 1/20 | 0.38 |
| ▸ | GHSR known ✓ | Q92847 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28306107 | 0.86 | MEN1 (0.45) | MEN1KMT2AKDM4ENPC1MITF | |
| Acetic Acid SCHEMBL28306148 | 0.78 | SLC18A3 (0.44) | MEN1KMT2AKDM4ENPC1MITF | |
| SCHEMBL8807231 | 0.77 | CHRM3 (0.54) | MEN1KMT2AKDM4ENPC1MITF | |
| SCHEMBL28891615 | 0.73 | MEN1 (0.54) | MEN1KMT2AKDM4ENPC1MITF | |
| SCHEMBL13681469 | 0.71 | OPRD1 (0.49) | MEN1KMT2AKDM4ENPC1MITF | |
| Acetic Acid SCHEMBL2256879 | 0.71 | NPSR1 (0.52) | MEN1KMT2ANPC1ALDH1A1RAB9A | |
| SCHEMBL3371883 | 0.70 | MITF (0.56) | MEN1KMT2AKDM4ENPC1MITF | |
| SCHEMBL4604800 | 0.69 | ALDH1A1 (0.64) | MEN1KMT2AKDM4ENPC1MITF | |
| SCHEMBL6601536 | 0.69 | KDM4E (0.64) | MEN1KMT2AKDM4ENPC1MITF | |
| SCHEMBL9776407 | 0.68 | LMNA (0.51) | MEN1KMT2AKDM4ENPC1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110018540-A | Stretched film and its manufacturing method | 柯尼卡美能达株式会社 | 2019-07-16 | — | — | CN | disclosed |
| CN-110014679-A | The manufacturing method of stretched film | 柯尼卡美能达株式会社 | 2019-07-16 | — | — | CN | disclosed |