Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28307440 | 0.87 | MAPT (0.33) | TP53MAPTPDE2APDE3ALMNA | |
| SCHEMBL28307461 | 0.86 | SDHB (0.39) | TP53MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL28306396 | 0.85 | ALDH1A1 (0.34) | TP53MAPTPDE2APDE3ALMNA | |
| SCHEMBL28307456 | 0.82 | SDHB (0.43) | TP53MAPTPDE2APDE3ALMNA | |
| SCHEMBL28307468 | 0.82 | PDE2A (0.32) | TP53MAPTPDE2APDE3AKMT2A | |
| SCHEMBL28307428 | 0.76 | DRD4 (0.30) | SIGMAR1 | |
| SCHEMBL28307435 | 0.76 | SDHB (0.33) | TP53MAPTPDE2APDE3ALMNA | |
| SCHEMBL28875023 | 0.75 | MAPT (0.39) | TP53MAPTSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL20985681 | 0.74 | SDHB (0.54) | TP53MAPTPDE2APDE3ALMNA | |
| SCHEMBL29975895 | 0.74 | SDHB (0.54) | TP53MAPTPDE2APDE3ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023292-A | Apoptosis inhibitor | 北京生命科学研究所 | 2019-07-16 | — | — | CN | disclosed |