Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDHB | P21912 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28875023 | 0.89 | MAPT (0.39) | SDHBMAPTTP53SMN1; SMN2HPGD | |
| SCHEMBL28306340 | 0.86 | TP53 (0.37) | MAPTTP53TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL22912252 | 0.85 | ALDH1A1 (0.34) | SDHBMAPTTP53TSHRSMN1; SMN2 | |
| SCHEMBL28307462 | 0.82 | SDHB (0.59) | SDHBMAPTTP53SMN1; SMN2HPGD | |
| SCHEMBL30526106 | 0.82 | SDHB (0.59) | SDHBMAPTTP53SMN1; SMN2HPGD | |
| SCHEMBL28306292 | 0.81 | SDHB (0.41) | SDHB | |
| SCHEMBL28307452 | 0.79 | SDHB (0.48) | SDHBMAPTTP53CYP1A2TSHR | |
| SCHEMBL28307448 | 0.77 | KDM4E (0.42) | SDHBMAPTTP53TSHRSMN1; SMN2 | |
| SCHEMBL28307434 | 0.77 | SDHB (0.63) | SDHBTP53CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL28306444 | 0.77 | SDHB (0.54) | SDHBTP53CYP1A2TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023292-A | Apoptosis inhibitor | 北京生命科学研究所 | 2019-07-16 | — | — | CN | disclosed |