Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDHB | P21912 | 1/20 | 0.63 |
| ▸ | SYK | P43405 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | STAT1 | P42224 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28874910 | 0.89 | SDHB (0.51) | SDHBHPGDSMN1; SMN2MITFS1PR4 | |
| SCHEMBL28306393 | 0.85 | SYK (0.46) | SDHBSYKKDM4EMEN1KMT2A | |
| SCHEMBL28306459 | 0.81 | SDHB (0.41) | SDHBSYKHPGDS1PR4LMNA | |
| SCHEMBL28874912 | 0.81 | SDHB (0.58) | SDHBHPGDSMN1; SMN2S1PR4LMNA | |
| SCHEMBL28307453 | 0.80 | SDHB (0.63) | SDHBHPGDSMN1; SMN2MITFS1PR4 | |
| SCHEMBL28306273 | 0.80 | NT5E (0.43) | SDHBHPGDSMN1; SMN2MITFS1PR4 | |
| SCHEMBL28874911 | 0.79 | HSD17B10 (0.55) | SDHBHPGDSMN1; SMN2MITFS1PR4 | |
| SCHEMBL19805689 | 0.77 | SDHB (1.00) | SDHBHPGDSMN1; SMN2MITFS1PR4 | |
| SCHEMBL28307459 | 0.77 | SDHB (0.60) | SDHBHPGDSMN1; SMN2S1PR4LMNA | |
| SCHEMBL6716512 | 0.77 | SDHB (0.65) | SDHBSYKLMNAHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023292-A | Apoptosis inhibitor | 北京生命科学研究所 | 2019-07-16 | — | — | CN | disclosed |