Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDHB | P21912 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28306273 | 0.86 | NT5E (0.43) | SDHBHSD17B10KDM4ELMNAPOLB | |
| SCHEMBL28874911 | 0.85 | HSD17B10 (0.55) | SDHBHSD17B10KDM4ELMNAPOLB | |
| SCHEMBL28874912 | 0.85 | SDHB (0.58) | SDHBHSD17B10KDM4ELMNAPOLB | |
| SCHEMBL28306393 | 0.84 | SYK (0.46) | SDHBHSD17B10KDM4ESYKMEN1 | |
| SCHEMBL28306266 | 0.81 | ALPL (0.45) | SDHBHSD17B10KDM4ESYK | |
| SCHEMBL28306355 | 0.81 | SDHB (0.63) | SDHBHSD17B10KDM4ESYKLMNA | |
| SCHEMBL28307459 | 0.81 | SDHB (0.60) | SDHBHSD17B10KDM4ELMNAPOLB | |
| SCHEMBL28307443 | 0.81 | KDM4E (0.49) | SDHBHSD17B10KDM4ELMNAPOLB | |
| SCHEMBL28306275 | 0.79 | MAPT (0.47) | SDHBHSD17B10KDM4ESYKTP53 | |
| SCHEMBL28307430 | 0.79 | KDM4E (0.56) | HSD17B10KDM4ELMNAKMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023292-A | Apoptosis inhibitor | 北京生命科学研究所 | 2019-07-16 | — | — | CN | disclosed |