Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDHB | P21912 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | LOX | P28300 | 1/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28306275 | 0.87 | MAPT (0.47) | SDHBMAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28874911 | 0.86 | HSD17B10 (0.55) | SDHBMAPTCYP1A2CYP2C19HSD17B10 | |
| SCHEMBL28307429 | 0.84 | SDHB (0.60) | SDHBMAPTLOXLOXL2CYP1A2 | |
| SCHEMBL28306273 | 0.82 | NT5E (0.43) | SDHBMAPTHSD17B10KDM4EADORA2A | |
| SCHEMBL28306459 | 0.81 | SDHB (0.41) | SDHBCYP2C19HSD17B10KDM4ECYP3A4 | |
| SCHEMBL28874912 | 0.81 | SDHB (0.58) | SDHBMAPTCYP1A2CYP2C19HSD17B10 | |
| SCHEMBL28306393 | 0.78 | SYK (0.46) | SDHBMAPTHSD17B10KDM4EMAPK1 | |
| SCHEMBL28306266 | 0.78 | ALPL (0.45) | SDHBHSD17B10KDM4EADORA2A | |
| SCHEMBL28306355 | 0.77 | SDHB (0.63) | SDHBMAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28307443 | 0.77 | KDM4E (0.49) | SDHBMAPTCYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023292-A | Apoptosis inhibitor | 北京生命科学研究所 | 2019-07-16 | — | — | CN | disclosed |