Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDHB | P21912 | 9/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 7/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.38 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 3/20 | 0.38 |
| ▸ | STAT1 | P42224 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28306356 | 0.90 | SDHB (0.35) | SDHBNPSR1LMNAHPGDKMT2A | |
| SCHEMBL28910510 | 0.87 | TP53 (0.39) | SDHBLMNAHPGDKMT2ATP53 | |
| SCHEMBL28306298 | 0.83 | SDHB (0.50) | SDHBNPSR1LMNAHPGDKMT2A | |
| SCHEMBL28307434 | 0.83 | SDHB (0.63) | SDHBNPSR1LMNAHPGDKMT2A | |
| SCHEMBL28306444 | 0.82 | SDHB (0.54) | SDHBNPSR1LMNAHPGDKMT2A | |
| SCHEMBL28306456 | 0.82 | SDHB (0.64) | SDHBNPSR1LMNAHPGDKMT2A | |
| SCHEMBL30526106 | 0.82 | SDHB (0.59) | SDHBNPSR1LMNAHPGDKMT2A | |
| SCHEMBL28307462 | 0.82 | SDHB (0.59) | SDHBNPSR1LMNAHPGDKMT2A | |
| SCHEMBL20985722 | 0.80 | SDHB (0.73) | SDHB | |
| SCHEMBL28307452 | 0.79 | SDHB (0.48) | SDHBNPSR1LMNAHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023292-A | Apoptosis inhibitor | 北京生命科学研究所 | 2019-07-16 | — | — | CN | disclosed |