Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | SDHB | P21912 | 9/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28306356 | 0.87 | SDHB (0.35) | TP53SDHBMAPTHPGDMEN1 | |
| SCHEMBL28306419 | 0.87 | SDHB (0.46) | TP53SMN1; SMN2SDHBKDM4EALDH1A1 | |
| SCHEMBL28910522 | 0.87 | KDM4E (0.34) | SMN1; SMN2MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL20985627 | 0.81 | SDHB (0.54) | TP53SMN1; SMN2SDHB | |
| SCHEMBL28307450 | 0.74 | SDHB (0.39) | TP53SMN1; SMN2SDHBKDM4EHPGD | |
| SCHEMBL28306288 | 0.74 | — | — | |
| SCHEMBL28307468 | 0.73 | PDE2A (0.32) | TP53MAPTKMT2A | |
| SCHEMBL29976562 | 0.73 | SDHB (0.69) | TP53SMN1; SMN2SDHBMAPTTDP1 | |
| SCHEMBL19805748 | 0.73 | SDHB (0.69) | TP53SMN1; SMN2SDHBMAPTTDP1 | |
| SCHEMBL28306298 | 0.70 | SDHB (0.50) | TP53SMN1; SMN2SDHBMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023292-B | Apoptosis inhibitors | 北京生命科学研究所 | 2022-10-04 | — | — | CN | disclosed |