SCHEMBL28306702

SCHEMBL28306702

Cc1ccccc1C(CC(=O)O)(C(=O)O)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.49
HIF1A Q16665 1/20 0.49
CHRM2 P08172 1/20 0.38
CHRM1 P11229 1/20 0.38
CHRM3 P20309 1/20 0.38
OPRM1 P35372 5/20 0.37
DRD3 P35462 3/20 0.37
DRD4 P21917 2/20 0.37
DRD2 P14416 1/20 0.37
CYP1A2 P05177 3/20 0.36
PTGS2 P35354 1/20 0.36
CYP2D6 P10635 1/20 0.35
GRIN2D O15399 2/20 0.35
GRIN1 Q05586 2/20 0.35
GRIN2A Q12879 2/20 0.35
GRIN2B Q13224 2/20 0.35
GRIN2C Q14957 2/20 0.35
OPRD1 P41143 2/20 0.35
CACNA1F O60840 1/20 0.35
ABCB1 P08183 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2220775 0.91 CYP2C19 (0.44) CYP2C19HIF1ACYP1A2PTGS2CYP2D6
SCHEMBL374784 0.82 CYP2C19 (0.57) CYP2C19HIF1ACHRM2CHRM1CHRM3
SCHEMBL28306699 0.80 KCNN4 (0.50) CYP2C19HIF1ACYP1A2PTGS2KMT2A
SCHEMBL28306690 0.80 KCNN4 (0.50) CYP2C19HIF1ACYP1A2PTGS2KMT2A
SCHEMBL28306747 0.80 POLB (0.45) CYP2C19HIF1AOPRM1DRD3DRD2
SCHEMBL28305527 0.79 CYP2C19 (0.52) CYP2C19HIF1ACHRM2CHRM1CHRM3
SCHEMBL20564089 0.78 ITGB3 (0.40) CHRM2SMN1; SMN2POLBALDH1A1TSHR
SCHEMBL29279074 0.78 TDP1 (0.47) CYP2C19HIF1ACYP1A2CYP2D6KMT2A
SCHEMBL28305534 0.78 CYP2C19 (0.42) CYP2C19HIF1ACHRM2CHRM1CHRM3
SCHEMBL29178237 0.77 CYP2C19 (0.44) CYP2C19HIF1APTGS2CYP2D6SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117567225-A Method for preparing dicarboxylic acid compound from olefin 徐州医科大学 2024-02-20 CN disclosed
CN-110028403-B Method for synthesizing succinic acid compound 四川大学 2020-08-11 CN disclosed
CN-110028403-A A kind of method of synthesizing succinic acid class compound 四川大学 2019-07-19 CN disclosed