SCHEMBL2220775

SCHEMBL2220775

Cc1ccccc1C(CC(=O)O)(C(=O)O)c1ccccc1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.44
HIF1A Q16665 2/20 0.44
POLB P06746 1/20 0.37
ITGB3 P05106 2/20 0.37
ITGAV P06756 2/20 0.37
ITGB1 P05556 1/20 0.37
ITGA5 P08648 1/20 0.37
KDM4E B2RXH2 3/20 0.36
ALDH1A1 P00352 2/20 0.36
GAA P10253 1/20 0.36
ATM Q13315 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ERCC5 P28715 1/20 0.36
FEN1 P39748 1/20 0.36
LMNA P02545 2/20 0.36
CTNNB1 P35222 1/20 0.35
WNT3A P56704 1/20 0.35
SLC13A5 Q86YT5 1/20 0.35
PTGS2 P35354 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28306702 0.91 CYP2C19 (0.49) CYP2C19HIF1APOLBITGB3ITGAV
SCHEMBL20564089 0.82 ITGB3 (0.40) POLBITGB3ITGAVITGB1ITGA5
SCHEMBL29178237 0.81 CYP2C19 (0.44) CYP2C19HIF1APOLBITGB3ITGAV
SCHEMBL20564736 0.80 HIF1A (0.43) CYP2C19HIF1APOLBKDM4EALDH1A1
SCHEMBL28892811 0.80 CYP2C19 (0.39) CYP2C19KDM4EALDH1A1GAAATM
SCHEMBL20564455 0.80 HDAC3 (0.41) ITGB3ITGAVALDH1A1NPSR1CTNNB1
SCHEMBL585411 0.79 CYP2C19 (0.50) CYP2C19HIF1APOLBITGB3ITGAV
SCHEMBL4207406 0.79 AKR1B1 (0.44) CYP2C19HIF1APOLBKDM4EALDH1A1
SCHEMBL20563197 0.78 HDAC3 (0.41) ITGB3ITGAVALDH1A1NPSR1TSHR
SCHEMBL8496808 0.78 AKR1B1 (0.41) CYP2C19HIF1AALDH1A1ERCC5FEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3625284-B1 POLYESTER COPOLYMER AVANTIUM KNOWLEDGE CENTRE BV (NL) 2025-05-07 EP disclosed
EP-3625283-B1 POLYESTER COPOLYMER AVANTIUM KNOWLEDGE CENTRE BV (NL) 2025-05-07 EP disclosed
US-11548980-B2 Polyester copolymer AVANTIUM KNOWLEDGE CENTRE B.V. (NL) 2023-01-10 US disclosed
CN-115109430-A Pigment and preparation method thereof 宁夏彩妍科技有限公司 2022-09-27 CN disclosed
US-11306179-B2 Polyester copolymer AVANTIUM KNOWLEDGE CENTRE B.V. (NL) 2022-04-19 US disclosed
US-20210403640-A1 Polyester Copolymer AVANTIUM KNOWLEDGE CENTRE B.V. (NL) 2021-12-30 US disclosed
US-20210139645-A1 Polyester Copolymer AVANTIUM KNOWLEDGE CENTRE B.V. (NL) 2021-05-13 US disclosed
EP-3625283-A1 POLYESTER COPOLYMER Avantium Knowledge Centre B.V. (NL) 2020-03-25 EP disclosed
EP-3625284-A1 POLYESTER COPOLYMER Avantium Knowledge Centre B.V. (NL) 2020-03-25 EP disclosed
WO-2018211133-A1 POLYESTER COPOLYMER AVANTIUM KNOWLEDGE CENTRE B.V. (NL) 2018-11-22 WO disclosed
WO-2018211132-A1 POLYESTER COPOLYMER AVANTIUM KNOWLEDGE CENTRE B.V. (NL) 2018-11-22 WO disclosed
US-9211510-B2 Method for producing nanoparticles by forced ultrathin film rotary processing M. TECHNIQUE CO., LTD. (JP) 2015-12-15 US disclosed
US-8592498-B2 Method for producing organic compound and organic compound obtained by the method M. TECHNIQUE CO., LTD. (JP) 2013-11-26 US disclosed
US-20110178199-A1 METHOD FOR PRODUCING ORGANIC COMPOUND AND ORGANIC COMPOUND OBTAINED BY THE METHOD M. TECHNIQUE CO., LTD. (JP) 2011-07-21 US disclosed
US-7728139-B2 Solvent-free process for the preparation of diketopyrrolopyrrole derivatives MCA TECHNOLOGIES GMBH (CH) 2010-06-01 US disclosed
US-20060246023-A1 for use as latent pigments; photocopiers MCA TECHNOLOGIES GMBH (CH) 2006-11-02 US disclosed
US-5492564-A HIGH OPACITY, COLORFASTNESS CIBA-GEIGY CORPORATION (US) 1996-02-20 US disclosed
US-4749795-A Phenyl substituted pyrrolinones CIBA-GEIGY CORPORATION (US) 1988-06-07 US disclosed
US-4720305-A Mixtures of pigments CIBA-GEIGY CORPORATION (US) 1988-01-19 US disclosed
US-4681971-A Phenyl substituted aminodicarboxylate esters CIBA-GEIGY CORPORATION (US) 1987-07-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060246023-A1 for use as latent pigments; photocopiers XPA, PPOX, ALDH1A2 CYP2C19 344/4885HIF1A 2096/4885POLB 1365/4885
US-20110178199-A1 METHOD FOR PRODUCING ORGANIC COMPOUND AND ORGANIC COMPOUND OBTAINED BY THE METHOD OR10J3, PORCN, ABCG2 CYP2C19 368/4885HIF1A 4823/4885POLB 1516/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.