SCHEMBL29178237

SCHEMBL29178237

Cc1ccccc1C(CC(=O)O)(CC(=O)O)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.44
HIF1A Q16665 2/20 0.44
POLB P06746 1/20 0.37
ALDH1A1 P00352 3/20 0.37
TSHR P16473 2/20 0.37
ITGB3 P05106 2/20 0.37
ITGAV P06756 2/20 0.37
ITGB1 P05556 1/20 0.37
ITGA5 P08648 1/20 0.37
KDM4E B2RXH2 2/20 0.36
GAA P10253 1/20 0.36
ATM Q13315 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ERCC5 P28715 1/20 0.36
FEN1 P39748 1/20 0.36
LMNA P02545 1/20 0.36
SLC13A5 Q86YT5 2/20 0.36
FFAR1 O14842 1/20 0.36
CTNNB1 P35222 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2220775 0.81 CYP2C19 (0.44) CYP2C19HIF1APOLBALDH1A1TSHR
SCHEMBL585411 0.79 CYP2C19 (0.50) CYP2C19HIF1APOLBALDH1A1TSHR
SCHEMBL28306702 0.77 CYP2C19 (0.49) CYP2C19HIF1APOLBALDH1A1TSHR
SCHEMBL2387498 0.74 HIF1A (0.57) CYP2C19HIF1AALDH1A1TSHRSLC13A5
SCHEMBL20563882 0.74 MYC (0.42) POLBALDH1A1TSHRKDM4EGAA
SCHEMBL31503044 0.74 TSHR (0.39) POLBALDH1A1TSHRKDM4EGAA
SCHEMBL2320019 0.74 HIF1A (0.41) CYP2C19HIF1APOLBALDH1A1TSHR
SCHEMBL30951242 0.74 P2RX7 (0.40) ALDH1A1GAA
Citric Acid SCHEMBL5874613 0.74 ALDH1A1 (0.46) CYP2C19HIF1AALDH1A1KDM4ELMNA
Citric Acid SCHEMBL27897976 0.73 ALDH1A1 (0.60) CYP2C19HIF1AALDH1A1KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117247317-A Based on CO 2 Method for synthesizing dicarboxylic acid/tricarboxylic acid compound 四川大学 2023-12-19 CN disclosed