Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28307763 | 0.91 | NCF1 (0.39) | KDM4EMAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL738596 | 0.87 | MAPT (0.52) | KDM4EMAPTPOLBCYP3A4MEN1 | |
| SCHEMBL20593896 | 0.81 | KDM4E (0.42) | KDM4EMAPTPOLBERN1CYP3A4 | |
| SCHEMBL28307761 | 0.77 | LMNA (0.41) | KDM4EMAPTCYP3A4MEN1KMT2A | |
| SCHEMBL736202 | 0.75 | NCF1 (0.50) | KDM4EMAPTCYP3A4MEN1KMT2A | |
| SCHEMBL30098629 | 0.75 | NCF1 (0.50) | KDM4EMAPTCYP3A4MEN1KMT2A | |
| SCHEMBL30129911 | 0.74 | KDM4E (0.58) | KDM4EMAPTPOLBERN1CYP3A4 | |
| SCHEMBL2265617 | 0.74 | KDM4E (0.58) | KDM4EMAPTPOLBERN1CYP3A4 | |
| SCHEMBL20593899 | 0.72 | NCF1 (0.41) | KDM4EMAPTCYP1A2ACACBSMN1; SMN2 | |
| SCHEMBL30018921 | 0.72 | NCF1 (0.41) | KDM4EMAPTCYP1A2ACACBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106661031-B | Pyrrolopyrimidine compounds or its salt, pharmaceutical composition and application containing it | 大鹏药品工业株式会社 | 2019-07-23 | — | — | CN | disclosed |