SCHEMBL2265617

SCHEMBL2265617

Fc1cccc2ncccc12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.58
MAPT P10636 2/20 0.58
LMNA P02545 3/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
HTT P42858 2/20 0.50
HSP90AA1 P07900 1/20 0.50
HSP90AB1 P08238 1/20 0.50
BLM P54132 1/20 0.50
HIF1A Q16665 1/20 0.50
POLB P06746 1/20 0.48
MPI P34949 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
CYP3A4 P08684 2/20 0.47
ALDH1A1 P00352 2/20 0.44
ERN1 O75460 1/20 0.44
P2RX7 Q99572 1/20 0.44
NCF1 P14598 1/20 0.43
CYP1A2 P05177 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30129911 1.00 KDM4E (0.58) KDM4EMAPTLMNAMEN1KMT2A
SCHEMBL1054409 0.84 NCF1 (0.56) KDM4EMAPTLMNAMEN1KMT2A
SCHEMBL30948576 0.84 NCF1 (0.56) KDM4EMAPTLMNAMEN1KMT2A
SCHEMBL4067917 0.82 KDM4E (0.57) KDM4EMAPTLMNAPOLBCYP3A4
SCHEMBL20593896 0.77 KDM4E (0.42) KDM4EMAPTLMNAMEN1KMT2A
SCHEMBL198641 0.76 MAPT (0.64) KDM4EMAPTLMNAMEN1KMT2A
SCHEMBL4054902 0.76 KDM4E (0.62) KDM4EMAPTLMNAMEN1KMT2A
SCHEMBL30387307 0.76 KDM4E (0.62) KDM4EMAPTLMNAMEN1KMT2A
SCHEMBL17838995 0.75 NR4A2 (0.62) KDM4EMAPTMEN1KMT2AMPI
SCHEMBL217044 0.75 MAPT (1.00) KDM4EMAPTLMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116925153-A Preparation method and application of fluorine-containing metal complex catalyst 浙江诺亚氟化工有限公司 2023-10-24 CN claimed
CN-108107142-B Analysis method of surfactant in wax removal water 上海微谱化工技术服务有限公司 2020-05-22 CN claimed
US-10224485-B2 Process for preparing a crystalline organic semiconductor material BASF SE (DE) 2019-03-05 US claimed
US-20170012208-A1 ORGANIC SEMICONDUCTOR FORMULATIONS USINVEST LLC 2017-01-12 US claimed
CN-116925153-B Preparation method and application of fluorine-containing metal complex catalyst 浙江诺亚氟化工有限公司 2025-09-05 CN disclosed
CN-113891879-B 3, 6-Disubstituted-2-pyridine aldoxime skeleton 国家科学研究中心 2025-03-04 CN disclosed
EP-3838900-B1 3-ARYLOXY-3-ARYL-PROPYLAMINE COMPOUND AND USES THEREOF ZHANGZHOU PIEN TZE HUANG PHARM (CN) 2025-02-12 EP disclosed
US-12209090-B2 3,6-disubstituted-2-pyridinaldoxime scaffolds CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2025-01-28 US disclosed
US-20240148744-A1 SULFONAMIDES AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES ZOETIS LLC 2024-05-09 US disclosed
CN-112654616-B 3-aryloxy-3-aryl-propylamines and application thereof 漳州片仔癀药业股份有限公司 2024-03-12 CN disclosed
EP-4291555-A1 SULFONAMIDES AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES Celgene Corporation (US) 2023-12-20 EP disclosed
WO-2023212565-A2 MOLECULAR EDITING OF MULTIPLE C-H BONDS BY LEVERAGING RECOGNITION OF DISTANCE, GEOMETRY AND CHIRALITY THE SCRIPPS RESEARCH INSTITUTE (US) 2023-11-02 WO disclosed
EP-0579695-A1 REISSERT COMPOUNDS AS ANTI-HIV AGENTS THE UPJOHN COMPANY (US) 1994-01-26 EP disclosed
WO-1993013071-A1 SPECTROPHOTOMETRIC METHODS FOR ASSAYING TOTAL MERCAPTANS, REDUCED GLUTATHIONE (GSH) AND MERCAPTANS OTHER THAN GSH IN AN AQUEOUS MEDIUM, REAGENTS AND KITS FOR IMPLEMENTING SAME BIOXYTECH (FR) 1993-07-08 WO disclosed
WO-1992016508-A1 REISSERT COMPOUNDS AS ANTI-HIV AGENTS THE UPJOHN COMPANY (US) 1992-10-01 WO disclosed
EP-0375658-A1 Quinoline derivatives and processes for preparation thereof Dainippon Pharmaceutical Co., Ltd. (JP) 1990-06-27 EP disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240148744-A1 SULFONAMIDES AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES ARSA, MRPS2, SULT2A1 KDM4E 4149/4885MAPT 441/4885LMNA 1006/4885
US-12209090-B2 3,6-disubstituted-2-pyridinaldoxime scaffolds XDH, TPX2, CYP4X1 KDM4E 1634/4885MAPT 2295/4885LMNA 1848/4885
US-10224485-B2 Process for preparing a crystalline organic semiconductor material STOM, SPOP, TTR KDM4E 3646/4885MAPT 150/4885LMNA 2511/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.