Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | SDHB | P21912 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30526106 | 0.79 | SDHB (0.59) | KDM4EHSD17B10MAPK1USP2TP53 | |
| SCHEMBL28307462 | 0.79 | SDHB (0.59) | KDM4EHSD17B10MAPK1USP2TP53 | |
| SCHEMBL28307461 | 0.77 | SDHB (0.39) | KDM4EHSD17B10USP2TP53LMNA | |
| SCHEMBL30526113 | 0.77 | SDHB (0.69) | KDM4EHSD17B10MAPK1USP2ALDH1A1 | |
| SCHEMBL19806068 | 0.77 | SDHB (0.69) | KDM4EHSD17B10MAPK1USP2ALDH1A1 | |
| SCHEMBL28307452 | 0.76 | SDHB (0.48) | KDM4EHSD17B10TP53LMNATSHR | |
| SCHEMBL28307434 | 0.75 | SDHB (0.63) | KDM4EHSD17B10TP53LMNAHTT | |
| SCHEMBL28306444 | 0.74 | SDHB (0.54) | KDM4EHSD17B10MAPK1TP53LMNA | |
| SCHEMBL28306456 | 0.74 | SDHB (0.64) | KDM4EHSD17B10TP53LMNAHTT | |
| SCHEMBL28306298 | 0.73 | SDHB (0.50) | HSD17B10MAPK1TP53LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023292-A | Apoptosis inhibitor | 北京生命科学研究所 | 2019-07-16 | — | — | CN | disclosed |