Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.37 |
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | DRD3 | P35462 | 3/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM6B | O15054 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19805960 | 0.72 | SDHB (0.52) | KDM4EALDH1A1MAPTSMN1; SMN2HPGD | |
| SCHEMBL28874911 | 0.70 | HSD17B10 (0.55) | KDM4EALDH1A1MAPTSMN1; SMN2HPGD | |
| SCHEMBL28234513 | 0.69 | HIF1A (0.35) | KDM4EALDH1A1ADORA2AADORA1LMNA | |
| SCHEMBL28307430 | 0.69 | KDM4E (0.56) | KDM4EALDH1A1MAPTSMN1; SMN2HPGD | |
| SCHEMBL28307443 | 0.68 | KDM4E (0.49) | KDM4EALDH1A1MAPTSMN1; SMN2HPGD | |
| SCHEMBL5483640 | 0.68 | ALDH1A1 (0.46) | KDM4EALDH1A1MAPTSMN1; SMN2HPGD | |
| SCHEMBL27344382 | 0.67 | GRM4 (0.31) | — | |
| SCHEMBL28306273 | 0.66 | NT5E (0.43) | KDM4EALDH1A1MAPTSMN1; SMN2HPGD | |
| SCHEMBL28874912 | 0.65 | SDHB (0.58) | KDM4EALDH1A1MAPTSMN1; SMN2HPGD | |
| SCHEMBL28306459 | 0.65 | SDHB (0.41) | KDM4EHPGDMAPK1HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023292-A | Apoptosis inhibitor | 北京生命科学研究所 | 2019-07-16 | — | — | CN | disclosed |