Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | PTPRC | P08575 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.50 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.47 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.47 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1368181 | 0.88 | TP53 (0.63) | TP53HTTSMN1; SMN2RAB9APTPRC | |
| SCHEMBL8821707 | 0.88 | MAOB (0.47) | TP53HTTSMN1; SMN2MAOBRAB9A | |
| SCHEMBL1760344 | 0.85 | TP53 (0.56) | TP53HTTPTPRCPTPN1NR4A2 | |
| SCHEMBL5988399 | 0.84 | TP53 (0.56) | TP53HTTMAOBRAB9AMAPT | |
| SCHEMBL29215741 | 0.84 | HCAR2 (0.59) | TP53HTTSMN1; SMN2RAB9AL3MBTL1 | |
| SCHEMBL3142013 | 0.84 | MRGPRX4 (0.56) | TP53HTTPTPRCPTPN1NR4A2 | |
| Hydrochloric Acid SCHEMBL6157166 | 0.84 | MAOB (0.63) | TP53HTTMAOBFOLH1 | |
| SCHEMBL6655381 | 0.83 | PTPRC (0.51) | SMN1; SMN2MAOBRAB9AGAAMAPT | |
| SCHEMBL5989548 | 0.81 | RXRA (0.59) | TP53HTTRAB9AMAPTL3MBTL1 | |
| SCHEMBL2552269 | 0.81 | FOLH1 (0.53) | TP53HTTPTPRCPTPN1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109988106-A | The aminated compounds for inhibiting SSAO/VAP-1 and its application in medicine | 广东东阳光药业有限公司 | 2019-07-09 | — | — | CN | disclosed |