Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.46 |
| ▸ | PTPRC | P08575 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28307883 | 0.88 | TP53 (0.55) | MAOBSMN1; SMN2GAAMAPTMAOA | |
| SCHEMBL1368181 | 0.75 | TP53 (0.63) | SMN1; SMN2RAB9AFOLH1NR4A2PTPRC | |
| SCHEMBL6655381 | 0.75 | PTPRC (0.51) | MAOBSMN1; SMN2GAAMAPTMAOA | |
| SCHEMBL28632277 | 0.74 | MAOB (0.67) | MAOBSMN1; SMN2GAAMAPTMAOA | |
| SCHEMBL3680999 | 0.74 | ALDH1A1 (0.55) | SMN1; SMN2RAB9AFOLH1ALDH1A1KDM4E | |
| SCHEMBL30159595 | 0.74 | HMGB1 (0.69) | FOLH1HMGB1ALDH1A1 | |
| SCHEMBL9221155 | 0.74 | HMGB1 (0.69) | FOLH1HMGB1ALDH1A1 | |
| SCHEMBL18586471 | 0.73 | HMGB1 (0.53) | SMN1; SMN2FOLH1NR4A2HMGB1ALDH1A1 | |
| SCHEMBL1760344 | 0.73 | TP53 (0.56) | FOLH1NR4A2PTPRCPTPN1MRGPRX4 | |
| SCHEMBL22912 | 0.73 | FOLH1 (0.59) | FOLH1HMGB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9176032-A | — | — | None | — | — | JP | disclosed |
| JP-63185995-A | — | — | None | — | — | JP | disclosed |
| JP-H09176032-A | CARCINOSTATIC | NIPPON FLOUR MILLS CO LTD | 1997-07-08 | — | — | JP | disclosed |
| JP-S63185995-A | NOVEL SUBSTANCE NF-861 AND NF-86II AND ALPHA-AMYLASE-INHIBITING AGENT CONTAINING NF-861 AND NF-86II | NIPPON SEIFUN KK | 1988-08-01 | — | — | JP | disclosed |
| US-4690891-A | CULTRUING SOIL BACILLUS, MUTANTS | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1987-09-01 | — | — | US | disclosed |