SCHEMBL28308392

SCHEMBL28308392

CS(=O)(=O)N1CCc2cc([Se]c3ccccc3)ccc21

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 4/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
NPC1 O15118 4/20 0.50
RAB9A P51151 4/20 0.50
GLA P06280 1/20 0.50
TSHR P16473 1/20 0.50
MMP13 P45452 1/20 0.50
CYP11B1 P15538 1/20 0.50
CYP11B2 P19099 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.49
HPGD P15428 1/20 0.48
TP53 P04637 1/20 0.46
MAPT P10636 1/20 0.46
PKM P14618 1/20 0.46
DRD3 P35462 1/20 0.45
HTR6 P50406 1/20 0.45
HRH3 Q9Y5N1 1/20 0.45
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
GAA P10253 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28309180 0.92 NLRP3 (0.48) POLBL3MBTL1NPC1RAB9ATSHR
SCHEMBL29594807 0.88 NPC1 (0.57) POLBL3MBTL1NPC1RAB9AGLA
SCHEMBL29593752 0.88 POLB (0.49) POLBL3MBTL1NPC1RAB9AGLA
SCHEMBL29594778 0.88 NPC1 (0.57) POLBL3MBTL1NPC1RAB9AGLA
SCHEMBL29593974 0.87 ALDH1A1 (0.48) POLBL3MBTL1NPC1RAB9AGLA
SCHEMBL28308395 0.86 TP53 (0.53) POLBTSHRCYP11B1CYP11B2TP53
SCHEMBL29594256 0.85 TP53 (0.55) POLBL3MBTL1RAB9AGLATSHR
SCHEMBL28308389 0.85 DRD3 (0.59) DRD3HTR6HRH3MEN1KMT2A
SCHEMBL29594581 0.84 NPC1 (0.55) POLBL3MBTL1NPC1RAB9AGLA
SCHEMBL29593773 0.84 MAPT (0.59) POLBL3MBTL1NPC1RAB9AGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110003080-A A kind of selenium-containing compound and preparation method thereof and purposes 成都大学 2019-07-12 CN disclosed