Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL137801 | 0.82 | TSHR (0.45) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8765961 | 0.78 | TSHR (0.42) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL21728849 | 0.78 | TSHR (0.38) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL28899828 | 0.78 | TSHR (0.45) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL29192563 | 0.76 | TSHR (0.39) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11380983 | 0.75 | TSHR (0.36) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL21728873 | 0.74 | TSHR (0.42) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL1901698 | 0.74 | TSHR (0.38) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8766001 | 0.74 | ALDH1A1 (0.42) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL27512565 | 0.73 | ALDH1A1 (0.42) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107266490-B | Acid hybrid monomers and dental material based on it | 义获嘉伟瓦登特公司 | 2019-07-02 | — | — | CN | disclosed |