SCHEMBL2830890

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2832075	0.93	SMN1; SMN2 (0.50)	ALDH1A1GABRA1GABRG2GABRB3GABRA5
	SCHEMBL2834187	0.90	S1PR3 (0.54)	ALDH1A1GABRA1GABRG2GABRB3GABRA5
	SCHEMBL2836985	0.89	GABRA1 (0.44)	ALDH1A1GABRA1GABRG2GABRB3GABRA5
	SCHEMBL2832416	0.88	BACE1 (0.48)	ALDH1A1GABRA1GABRG2GABRB3GABRA5
	SCHEMBL2837655	0.88	BACE1 (0.48)	ALDH1A1GABRA1GABRG2GABRB3GABRA5
	SCHEMBL2837649	0.87	S1PR3 (0.52)	ALDH1A1GABRA1GABRG2GABRB3GABRA5
	SCHEMBL19835545	0.84	SLC6A3 (0.51)	ALDH1A1SMN1; SMN2KDM4EMAPTLMNA
	SCHEMBL2833745	0.83	CYP1A2 (0.61)	ALDH1A1SMN1; SMN2KDM4EMAPTHPGD
	SCHEMBL23030228	0.83	ALDH1A1 (0.51)	ALDH1A1GABRA1GABRG2GABRB3GABRA5
	SCHEMBL2832069	0.81	ALDH1A1 (0.44)	ALDH1A1GABRA1GABRG2GABRB3GABRA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.