Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28309298 | 0.84 | ALDH1A1 (0.46) | ALDH1A1GLATSHRTP53PTGS2 | |
| SCHEMBL17333743 | 0.76 | TP53 (0.64) | ALDH1A1GLATSHRTP53LTB4R2 | |
| SCHEMBL21455840 | 0.72 | SMN1; SMN2 (0.48) | ALDH1A1GLATSHRTP53LTB4R2 | |
| SCHEMBL5595921 | 0.72 | TP53 (0.79) | ALDH1A1GLATSHRTP53LTB4R2 | |
| SCHEMBL1185690 | 0.70 | ALDH1A1 (0.76) | ALDH1A1GLATSHRTP53MEN1 | |
| SCHEMBL11518360 | 0.70 | TP53 (0.60) | ALDH1A1GLATSHRTP53LTB4R2 | |
| SCHEMBL17439411 | 0.70 | TP53 (0.60) | ALDH1A1GLATSHRTP53LTB4R2 | |
| SCHEMBL11529582 | 0.69 | L3MBTL1 (0.65) | ALDH1A1GLATSHRLTB4R2MEN1 | |
| SCHEMBL3772286 | 0.68 | TP53 (0.83) | ALDH1A1GLATSHRTP53LTB4R2 | |
| SCHEMBL22665374 | 0.68 | ALDH1A1 (0.50) | ALDH1A1GLATSHRTP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110072850-A | 3-sulfonyl-5-aminopyridine-2, 4-diol APJ agonists | 百时美施贵宝公司 | 2019-07-30 | — | — | CN | disclosed |