SCHEMBL28309352

SCHEMBL28309352

O=C(O)CNCCC(CCC(c1ccccc1)c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 9/20 0.47
CNR2 P34972 6/20 0.47
MTNR1A P48039 1/20 0.42
MTNR1B P49286 1/20 0.42
EPHX2 P34913 3/20 0.41
CASR P41180 2/20 0.38
HTR2A P28223 1/20 0.37
HRH1 P35367 1/20 0.37
KCNH2 Q12809 1/20 0.36
DPP4 P27487 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL329180 0.80 MTNR1A (0.58) CNR1CNR2MTNR1AMTNR1BEPHX2
SCHEMBL28308524 0.75 CNR1 (0.40) CNR1CNR2MTNR1AMTNR1BEPHX2
Glycine SCHEMBL27555842 0.74 MTNR1A (0.51) CNR1CNR2MTNR1AMTNR1BEPHX2
SCHEMBL16197845 0.72 MTNR1A (0.49) CNR1CNR2MTNR1AMTNR1BEPHX2
SCHEMBL663798 0.70 CNR1 (0.62) CNR1CNR2MTNR1AMTNR1BEPHX2
SCHEMBL181573 0.69 GRIN1 (0.52) CNR1CNR2MTNR1AMTNR1BEPHX2
SCHEMBL5846249 0.68 KCNH2 (0.58) CNR1CNR2MTNR1AMTNR1BEPHX2
SCHEMBL1321258 0.67 MTNR1A (0.54) CNR1CNR2MTNR1AMTNR1BEPHX2
SCHEMBL3674189 0.66 CYP2D6 (0.54) CNR1CNR2MTNR1AMTNR1BEPHX2
Hydrochloric Acid SCHEMBL5311014 0.66 MTNR1A (0.53) CNR1CNR2MTNR1AMTNR1BEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110072883-A The relevant peptide of therapeutic MOTS-C 科巴公司 2019-07-30 CN disclosed