Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 6/20 | 0.47 |
| ▸ | CNR2 | P34972 | 5/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1321258 | 0.94 | MTNR1A (0.54) | MTNR1AMTNR1BCNR1CNR2EPHX2 | |
| Hydrochloric Acid SCHEMBL5311014 | 0.92 | MTNR1A (0.53) | MTNR1AMTNR1BCNR1CNR2EPHX2 | |
| SCHEMBL329180 | 0.90 | MTNR1A (0.58) | MTNR1AMTNR1BCNR1CNR2EPHX2 | |
| Glycine SCHEMBL27555842 | 0.87 | MTNR1A (0.51) | MTNR1AMTNR1BCNR1CNR2EPHX2 | |
| SCHEMBL16197682 | 0.84 | BCAT2 (0.44) | — | |
| SCHEMBL5093255 | 0.81 | BCAT2 (0.51) | MTNR1AMTNR1B | |
| SCHEMBL16197842 | 0.80 | MTNR1A (0.46) | MTNR1AMTNR1BCNR1CNR2EPHX2 | |
| SCHEMBL663798 | 0.79 | CNR1 (0.62) | MTNR1AMTNR1BCNR1CNR2EPHX2 | |
| SCHEMBL5846249 | 0.78 | KCNH2 (0.58) | MTNR1AMTNR1BCNR1CNR2EPHX2 | |
| SCHEMBL7390885 | 0.78 | KCNH2 (0.53) | MTNR1AMTNR1BCNR1CNR2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2989119-A1 | USE OF INHIBITORY PEPTIDES FOR THE TREATMENT OF INFLAMMATORY DISEASES | Yeda Research and Development Co., Ltd. (IL) | 2016-03-02 | — | — | EP | disclosed |
| WO-2014174520-A1 | USE OF INHIBITORY PEPTIDES FOR THE TREATMENT OF INFLAMMATORY DISEASES | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2014-10-30 | — | — | WO | disclosed |