Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28229748 | 0.81 | NPC1 (0.59) | NPC1RAB9APOLBALDH1A1MAPT | |
| SCHEMBL7806735 | 0.79 | NPC1 (0.61) | NPC1RAB9APOLBALDH1A1MAPT | |
| SCHEMBL132682 | 0.78 | NPC1 (0.65) | NPC1RAB9APOLBALDH1A1MAPT | |
| SCHEMBL28042319 | 0.78 | NPC1 (0.65) | NPC1RAB9APOLBALDH1A1MAPT | |
| SCHEMBL1695124 | 0.78 | ALDH1A1 (0.55) | NPC1RAB9APOLBALDH1A1MAPT | |
| SCHEMBL27393789 | 0.78 | NPC1 (0.65) | NPC1RAB9APOLBALDH1A1MAPT | |
| Ammonia Solution, Strong SCHEMBL5933498 | 0.77 | NPC1 (0.62) | NPC1RAB9APOLBALDH1A1MAPT | |
| SCHEMBL13479729 | 0.75 | NPC1 (0.61) | NPC1RAB9APOLBALDH1A1MAPT | |
| SCHEMBL1723352 | 0.74 | NPC1 (0.65) | NPC1RAB9APOLBALDH1A1MAPT | |
| SCHEMBL27929994 | 0.74 | NPC1 (0.65) | NPC1RAB9APOLBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109912603-A | A kind of practical approach using N- methoxyamide as nitrogen source synthesizing new bioactive molecule | 苏州大学 | 2019-06-21 | — | — | CN | disclosed |