Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.59 |
| ▸ | RAB9A | P51151 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27469935 | 0.82 | RAB9A (0.59) | NPC1RAB9AALDH1A1POLBMAPT | |
| SCHEMBL30184258 | 0.81 | RAB9A (0.57) | NPC1RAB9AALDH1A1POLBMAPT | |
| SCHEMBL28309396 | 0.81 | NPC1 (0.57) | NPC1RAB9AALDH1A1POLBMAPT | |
| SCHEMBL6291676 | 0.80 | NPC1 (0.53) | NPC1RAB9AALDH1A1POLBMAPT | |
| SCHEMBL1723352 | 0.79 | NPC1 (0.65) | NPC1RAB9AALDH1A1POLBMAPT | |
| SCHEMBL27393789 | 0.79 | NPC1 (0.65) | NPC1RAB9AALDH1A1POLBMAPT | |
| SCHEMBL13479729 | 0.76 | NPC1 (0.61) | NPC1RAB9AALDH1A1POLBMAPT | |
| SCHEMBL6291619 | 0.76 | MAPT (0.51) | NPC1RAB9AALDH1A1POLBMAPT | |
| SCHEMBL1695124 | 0.76 | ALDH1A1 (0.55) | NPC1RAB9AALDH1A1POLBMAPT | |
| SCHEMBL28042319 | 0.76 | NPC1 (0.65) | NPC1RAB9AALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108349901-A | PHENYL DERIVATIVES AS CANNABINOID RECEPTOR 2 AGONISTS | 豪夫迈·罗氏有限公司 | 2018-07-31 | — | — | CN | disclosed |