SCHEMBL28309481

SCHEMBL28309481

C=C(CCC)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28291216 0.98 THRB (0.34) THRB
SCHEMBL28858564 0.82 THRB (0.41) THRB
SCHEMBL8747166 0.82 FAAH (0.42)
SCHEMBL28272992 0.71 THRB (0.35) THRB
SCHEMBL10289156 0.71
SCHEMBL9191214 0.70 THRB (0.38) THRB
SCHEMBL26070144 0.69
SCHEMBL28280487 0.69 THRB (0.46) THRB
SCHEMBL24290030 0.68
SCHEMBL28174288 0.68 THRB (0.32) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110158060-A A kind of multilayered structure and preparation method thereof 清华大学深圳研究生院 2019-08-23 CN claimed