Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | CHUK | O15111 | 1/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | PAK4 | O96013 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | LTK | P29376 | 1/20 | 0.35 |
| ▸ | GRK5 | P34947 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28309541 | 0.78 | IKBKB (0.38) | IKBKBCHUKDAPK3JAK2PRKD3 | |
| SCHEMBL554430 | 0.76 | LRRK2 (0.39) | IKBKBCHUKDAPK3JAK2PRKD3 | |
| SCHEMBL28308671 | 0.76 | CHEK1 (0.42) | IKBKBCHUKDAPK3JAK2PRKD3 | |
| SCHEMBL16542123 | 0.73 | NOTUM (0.36) | CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10824239 | 0.72 | TOP1 (0.40) | TOP1ALDH1A1LMNA | |
| SCHEMBL2977681 | 0.71 | ALDH1A1 (0.55) | LRRK2ALDH1A1MEN1CYP1A2CYP2C9 | |
| Iodide SCHEMBL27658785 | 0.70 | TOP1 (0.39) | TOP1ALDH1A1LMNA | |
| SCHEMBL15327834 | 0.69 | CDC7 (0.46) | IKBKBCHUKMAP2K1CLK4DYRK1B | |
| SCHEMBL59062 | 0.66 | CCNC (0.40) | IKBKBCHUKCDK8TACR1GSK3B | |
| SCHEMBL28198595 | 0.66 | LRRK2 (0.39) | IKBKBCHUKDAPK3JAK2PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109956898-B | Immunomodulator, preparation method and medical application thereof | 上海海雁医药科技有限公司 | 2021-03-26 | — | — | CN | disclosed |
| CN-109956898-A | Immunomodulator and its preparation method and purposes pharmaceutically | 上海海雁医药科技有限公司 | 2019-07-02 | — | — | CN | disclosed |