SCHEMBL2831061

SCHEMBL2831061

O=C(O)c1cccc(NS(=O)(=O)c2cccc(Cl)c2)c1

nearest known ligand 0.71

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PFKFB3 Q16875 1/20 0.71
PGR P06401 3/20 0.70
MEN1 O00255 4/20 0.70
KMT2A Q03164 4/20 0.70
POLB P06746 2/20 0.68
TSHR P16473 2/20 0.62
ALDH1A1 P00352 2/20 0.62
MAPT P10636 1/20 0.62
AKR1C3 P42330 1/20 0.61
USP2 O75604 1/20 0.60
THRB P10828 1/20 0.60
KDM4E B2RXH2 1/20 0.59
PTK2B Q14289 1/20 0.59
NPC1 O15118 1/20 0.58
RAB9A P51151 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
PKM P14618 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29875309 1.00 PFKFB3 (0.71) PFKFB3PGRMEN1KMT2APOLB
SCHEMBL29369447 1.00 PFKFB3 (0.71) PFKFB3PGRMEN1KMT2APOLB
SCHEMBL8251165 0.94 PFKFB3 (0.67) PFKFB3PGRMEN1KMT2APOLB
SCHEMBL2828714 0.88 MEN1 (0.74) PGRMEN1KMT2AMAPTTHRB
SCHEMBL5329565 0.87 PGR (0.80) PGRMEN1KMT2AMAPTPKM
SCHEMBL17331335 0.87 POLB (0.78) PFKFB3MEN1KMT2APOLBALDH1A1
SCHEMBL894613 0.86 POLB (0.82) PFKFB3MEN1KMT2APOLBALDH1A1
SCHEMBL787825 0.85 PFKFB3 (0.79) PFKFB3PGRMEN1KMT2APOLB
SCHEMBL788010 0.85 PFKFB3 (0.83) PFKFB3PGRMEN1KMT2APOLB
SCHEMBL29561210 0.85 POLB (0.71) PFKFB3PGRMEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250258104-A1 DIAGNOSTIC TEST KITS FOR SAMPLE PREPARATION AND ANALYSIS SCANWELL HEALTH INC (US) 2025-08-14 US claimed
US-12235217-B2 Diagnostic test kits for sample preparation and analysis SCANWELL HEALTH, INC. (US) 2025-02-25 US claimed
EP-4058775-A1 DIAGNOSTIC TEST KITS FOR SAMPLE PREPARATION AND ANALYSIS Scanwell Health, Inc. (US) 2022-09-21 EP claimed
CN-114981637-A Diagnostic test kit for sample preparation and analysis 斯肯威尔健康公司 2022-08-30 CN claimed
US-20210231574-A1 DIAGNOSTIC TEST KITS FOR SAMPLE PREPARATION AND ANALYSIS SCANWELL HEALTH, INC. 2021-07-29 US claimed
WO-2021097343-A1 DIAGNOSTIC TEST KITS FOR SAMPLE PREPARATION AND ANALYSIS SCANWELL HEALTH, INC. (US) 2021-05-20 WO claimed
US-20250258104-A1 DIAGNOSTIC TEST KITS FOR SAMPLE PREPARATION AND ANALYSIS SCANWELL HEALTH INC (US) 2025-08-14 US disclosed
EP-4587481-A1 PROCESS FOR CONJUGATION OF HYALURONIC ACID AND CONJUGATES OF HYALURONIC ACID SO OBTAINED GLYCOCORE PHARMA S.r.l. (IT) 2025-07-23 EP disclosed
WO-2025056689-A1 ELECTROCHEMICAL DETECTION OF MONOCHLORAMINE AND/OR AMMONIA PALINTEST LTD (GB) 2025-03-20 WO disclosed
US-12235217-B2 Diagnostic test kits for sample preparation and analysis SCANWELL HEALTH, INC. (US) 2025-02-25 US disclosed
WO-2024057154-A1 PROCESS FOR CONJUGATION OF HYALURONIC ACID AND CONJUGATES OF HYALURONIC ACID SO OBTAINED GLYCOCORE PHARMA S.R.L. (IT) 2024-03-21 WO disclosed
EP-4058775-A1 DIAGNOSTIC TEST KITS FOR SAMPLE PREPARATION AND ANALYSIS Scanwell Health, Inc. (US) 2022-09-21 EP disclosed
CN-114981637-A Diagnostic test kit for sample preparation and analysis 斯肯威尔健康公司 2022-08-30 CN disclosed
US-20100144762-A1 NOVEL SULFONAMIDES AS L-CPT1 INHIBITORS BLEICHER KONRAD 2010-06-10 US disclosed
US-7723538-B2 enzyme inhibitors of membrane-bound carnitine-dependent palmitoyltransferases (CPTs); inhibit gluconeogenesis and therefore counteract hyperglycemia; 4-(3-Benzenesulfonylamino-benzoylamino)-benzoic acid HOFFMANN-LA ROCHE INC. (US) 2010-05-25 US disclosed
EP-1891001-B1 SULFONAMIDE DERIVATIVES USEFUL AS LIVER CARNITINE PALMITOYL TRANSFERASE (L-CPTl) INHIBITORS HOFFMANN LA ROCHE (CH) 2010-05-05 EP disclosed
CN-101189210-A Sulfonamide derivatives useful as liver carnitine palmitoyl transferase (L-CPTl) inhibitors HOFFMANN LA ROCHE (CH) 2008-05-28 CN disclosed
EP-1891001-A1 SULFONAMIDE DERIVATIVES USEFUL AS LIVER CARNITINE PALMITOYL TRANSFERASE (L-CPTl) INHIBITORS F. Hoffmann-Roche AG (CH) 2008-02-27 EP disclosed
WO-2006131452-A1 SULFONAMIDE DERIVATIVES USEFUL AS LIVER CARNITINE PALMITOYL TRANSFERASE (L-CPTl) INHIBITORS F. HOFFMANN-LA ROCHE AG (CH) 2006-12-14 WO disclosed
US-20060276494-A1 Novel sulfonamides as L-CPT1 inhibitors F. HOFFMANN-LA ROCHE AG (CH) 2006-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060276494-A1 Novel sulfonamides as L-CPT1 inhibitors CPT1A, CPT1B, CPT2 PFKFB3 509/4885PGR 4545/4885MEN1 4442/4885
US-20100144762-A1 NOVEL SULFONAMIDES AS L-CPT1 INHIBITORS CPT1A, CPT1B, CPT2 PFKFB3 509/4885PGR 4545/4885MEN1 4442/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.