Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | CCR2 | P41597 | 11/20 | 0.56 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.49 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | PLA2G2E | Q9NZK7 | 1/20 | 0.43 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.43 |
| ▸ | CCR9 | P51686 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28310023 | 0.83 | KDM4E (0.68) | KDM4EALDH1A1HPGDHSD17B10CCR2 | |
| SCHEMBL28310029 | 0.81 | KDM4E (0.68) | KDM4EALDH1A1HPGDHSD17B10CCR2 | |
| SCHEMBL28827638 | 0.80 | HPGD (0.44) | KDM4EALDH1A1HPGDHSD17B10CCR2 | |
| SCHEMBL5162898 | 0.79 | PLA2G10 (0.55) | KDM4EALDH1A1HPGDCCR2GPR35 | |
| SCHEMBL28310030 | 0.79 | KDM4E (0.65) | KDM4EALDH1A1HPGDHSD17B10CCR2 | |
| SCHEMBL27938424 | 0.76 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10GPR35 | |
| SCHEMBL6308876 | 0.72 | CCR2 (0.69) | CCR2GPR35SRD5A1SRD5A2PLA2G2A | |
| SCHEMBL26581247 | 0.72 | CCR2 (0.62) | ALDH1A1CCR2GPR35CCR9 | |
| SCHEMBL9536869 | 0.72 | CCR2 (0.76) | KDM4EALDH1A1HPGDHSD17B10CCR2 | |
| SCHEMBL6302531 | 0.71 | CCR2 (1.00) | CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105367495-B | Piperlongumine containing seven membered lactams rings is similar to object and its preparation and application | 中国人民解放军第二军医大学 | 2019-07-23 | — | — | CN | disclosed |