Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27148100 | 0.79 | OPRM1 (0.51) | OPRM1MPO | |
| Verdiperstat SCHEMBL23225670 | 0.67 | MPO (0.58) | OPRM1MPO | |
| SCHEMBL23218008 | 0.62 | OPRM1 (0.46) | OPRM1MPO | |
| SCHEMBL29879357 | 0.61 | MPO (0.70) | OPRM1MPO | |
| SCHEMBL23217928 | 0.61 | OPRM1 (0.47) | OPRM1MPO | |
| Verdiperstat SCHEMBL1536607 | 0.60 | MPO (1.00) | OPRM1MPO | |
| SCHEMBL30426035 | 0.56 | MPO (0.51) | OPRM1MPO | |
| SCHEMBL13811847 | 0.53 | OPRM1 (0.37) | OPRM1MPO | |
| SCHEMBL9917279 | 0.52 | PIK3CD (0.49) | — | |
| SCHEMBL15723760 | 0.51 | MEN1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483492-A | Dipeptidyl peptidase i inhibitors | ASTRAZENECA AB | 2019-11-22 | — | — | CN | disclosed |
| CN-105980367-B | (2S) -N- [ (1S) -1-cyano-2-phenylethyl ] -1, 4-oxazepane-2-carboxamides as dipeptidyl peptidase I inhibitors | 阿斯利康(瑞典)有限公司 | 2019-08-23 | — | — | CN | disclosed |