Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALPG | P10696 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL29161110 | 0.97 | ALDH1A1 (0.37) | ALDH1A1KDM4ETDP1CYP3A4CYP2C9 | |
| Iodide SCHEMBL29161104 | 0.97 | ALDH1A1 (0.37) | ALDH1A1KDM4ETDP1CYP3A4CYP2C9 | |
| Fluoride Ion SCHEMBL29161107 | 0.97 | ALDH1A1 (0.37) | ALDH1A1KDM4ETDP1CYP3A4CYP2C9 | |
| Sulfuric Acid SCHEMBL27791166 | 0.92 | ALDH1A1 (0.34) | ALDH1A1KDM4ETDP1CYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL29161124 | 0.90 | THRB (0.37) | ALDH1A1KDM4ETDP1THRBTSHR | |
| Iodide SCHEMBL29161114 | 0.87 | THRB (0.37) | ALDH1A1KDM4ETDP1CYP3A4CYP2C9 | |
| Bromide SCHEMBL29161111 | 0.87 | THRB (0.37) | ALDH1A1KDM4ETDP1CYP3A4CYP2C9 | |
| Fluoride Ion SCHEMBL29161122 | 0.87 | THRB (0.37) | ALDH1A1KDM4ETDP1CYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL29161109 | 0.85 | ALDH1A1 (0.36) | ALDH1A1KDM4ETDP1CYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL27716000 | 0.85 | ALDH1A1 (0.34) | ALDH1A1KDM4ETDP1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117629699-A | Papermaking method for improving paper strength | 瑞辰星生物技术（广州）有限公司 | 2024-03-01 | — | — | CN | claimed |
| CN-119731226-A | Block copolymer, dispersant and coloring composition | 大塚化学株式会社 | 2025-03-28 | — | — | CN | disclosed |
| CN-119654360-A | Block copolymer, dispersant and coloring composition | 大塚化学株式会社 | 2025-03-18 | — | — | CN | disclosed |
| WO-2024116875-A1 | BLOCK COPOLYMER, DISPERSING AGENT, AND COLORED COMPOSITION | 大塚化学株式会社 | 2024-06-06 | — | — | WO | disclosed |
| WO-2024116876-A1 | BLOCK COPOLYMER, DISPERSANT, AND COLORING COMPOSITION | 大塚化学株式会社 | 2024-06-06 | — | — | WO | disclosed |
| CN-117629699-A | Papermaking method for improving paper strength | 瑞辰星生物技术（广州）有限公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-117586645-A | Coloring composition containing dioxazine pigment and color filter | 大塚化学株式会社 | 2024-02-23 | — | — | CN | disclosed |
| CN-110055818-A | A kind of paper making intensifier and the preparation method and application thereof | 济宁南天农科化工有限公司 | 2019-07-26 | — | — | CN | disclosed |