Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 3/20 | 0.38 |
| ▸ | PIM1 | P11309 | 2/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24950460 | 0.80 | FGFR1 (0.55) | SCN9APIM3PIM1FGFR1F2 | |
| SCHEMBL30201454 | 0.80 | FGFR1 (0.55) | SCN9APIM3PIM1FGFR1F2 | |
| SCHEMBL30201485 | 0.77 | SCN9A (0.48) | SCN9APIM3PIM1CSNK2A1PIM2 | |
| SCHEMBL30201463 | 0.77 | SCN9A (0.60) | SCN9AFGFR1F2F10PRSS1 | |
| SCHEMBL15687555 | 0.75 | CYP2A6 (0.50) | FGFR1KDM4EALDH1A1 | |
| SCHEMBL28311660 | 0.75 | LCK (0.40) | LCKFYNDAOFGFR1MCL1 | |
| SCHEMBL29280306 | 0.74 | SRD5A2 (0.49) | SCN9AFGFR1F2F10PRSS1 | |
| SCHEMBL29443120 | 0.72 | FGFR1 (0.68) | FGFR1RXRAALDH1A1HPGDHSD17B10 | |
| SCHEMBL2346413 | 0.72 | BIRC5 (0.53) | FGFR1ALDH1A1 | |
| SCHEMBL16056406 | 0.70 | MCL1 (0.42) | SCN9AFGFR1MCL1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110003169-A | GPR40 receptor agonist, method for preparing same, and pharmaceutical composition containing same as active ingredient | 株式会社LG化学 | 2019-07-12 | — | — | CN | disclosed |