Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | ADH5 | P11766 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6840246 | 0.88 | RXRA (0.47) | FGFR1NAPRTPIM3TBXAS1PIM1 | |
| SCHEMBL24950460 | 0.86 | FGFR1 (0.55) | SCN9AFGFR1PIM3PIM1F2 | |
| SCHEMBL30201454 | 0.86 | FGFR1 (0.55) | SCN9AFGFR1PIM3PIM1F2 | |
| SCHEMBL29280306 | 0.82 | SRD5A2 (0.49) | SCN9AFGFR1F2F10PRSS1 | |
| SCHEMBL30201463 | 0.82 | SCN9A (0.60) | SCN9AFGFR1F2F10PRSS1 | |
| SCHEMBL28311684 | 0.77 | SCN9A (0.44) | SCN9AFGFR1PIM3PIM1CSNK2A1 | |
| SCHEMBL26436213 | 0.76 | CYP19A1 (0.48) | NAPRTCYP19A1DYRK1ANR4A1NR4A2 | |
| SCHEMBL6840263 | 0.75 | HTR6 (0.58) | TBXAS1F2F10PRSS1MCL1 | |
| SCHEMBL25259848 | 0.75 | ROCK2 (0.63) | FGFR1PIM3PIM1 | |
| SCHEMBL1613814 | 0.74 | CDC7 (0.54) | CYP19A1CDC7CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117729914-A | Serotonin 5-HT2B inhibiting compounds | 硕腾服务有限责任公司 | 2024-03-19 | — | — | CN | disclosed |
| WO-2023009330-A1 | SEROTONIN 5-HT2B INHIBITORY COMPOUNDS | ZOETIS SERVICES LLC (US) | 2023-02-02 | — | — | WO | disclosed |