Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.60 |
| ▸ | MGLL | Q99685 | 3/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | BAD | Q92934 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | F10 | P00742 | 2/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL121755 | 0.88 | MGLL (0.56) | SCN9AMGLLKCNH2BCL2L1BAD | |
| SCHEMBL24950460 | 0.86 | FGFR1 (0.55) | SCN9AF2F10PRSS1FGFR1 | |
| SCHEMBL30201454 | 0.86 | FGFR1 (0.55) | SCN9AF2F10PRSS1FGFR1 | |
| SCHEMBL29280306 | 0.85 | SRD5A2 (0.49) | SCN9AMGLLKCNH2F2F10 | |
| SCHEMBL18002655 | 0.83 | KDM4E (0.54) | SCN9AKCNH2KDM4EALDH1A1MAPT | |
| SCHEMBL30201485 | 0.82 | SCN9A (0.48) | SCN9AF2F10PRSS1FGFR1 | |
| SCHEMBL2610323 | 0.78 | KCNH2 (0.48) | SCN9AMGLLKCNH2KDM4EALDH1A1 | |
| SCHEMBL2610321 | 0.78 | KCNH2 (0.47) | SCN9AMGLLKCNH2KDM4EALDH1A1 | |
| SCHEMBL28311684 | 0.77 | SCN9A (0.44) | SCN9AF2F10PRSS1FGFR1 | |
| SCHEMBL6840200 | 0.76 | RXRA (0.47) | SCN9AMGLLKCNH2FGFR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117729914-A | Serotonin 5-HT2B inhibiting compounds | 硕腾服务有限责任公司 | 2024-03-19 | — | — | CN | disclosed |
| WO-2023009330-A1 | SEROTONIN 5-HT2B INHIBITORY COMPOUNDS | ZOETIS SERVICES LLC (US) | 2023-02-02 | — | — | WO | disclosed |