Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9320071 | 0.87 | TTR (0.49) | TTRMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL23212346 | 0.83 | TTR (0.57) | TTRMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL11107372 | 0.81 | KEAP1 (0.53) | TTRMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL11101186 | 0.81 | TTR (0.72) | TTRMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL8675454 | 0.81 | TTR (0.52) | TTRMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL11039554 | 0.81 | ELANE (0.55) | TTRMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL28707279 | 0.81 | TYMS (0.47) | TTRMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL29019962 | 0.80 | KCNA3 (0.51) | TTRMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL28341314 | 0.80 | ELANE (0.57) | TTRMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL8040042 | 0.79 | ALDH1A1 (0.60) | TTRMAPTALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104271158-B | The conjoint therapy and application thereof of a variety of anti-human CSF-1R antibody | 霍夫曼-拉罗奇有限公司 | 2019-08-16 | — | — | CN | disclosed |