Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | TTR | P02766 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | EGFR | P00533 | 2/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2460415 | 0.93 | ELANE (0.54) | ELANEMAOATTRKDM4EHPGD | |
| SCHEMBL11039554 | 0.88 | ELANE (0.55) | ELANEMAOATTRKDM4EHPGD | |
| SCHEMBL11102131 | 0.86 | ELANE (0.53) | ELANEMAOATTRKDM4EHPGD | |
| SCHEMBL11101186 | 0.85 | TTR (0.72) | ELANEMAOATTRKDM4EHPGD | |
| SCHEMBL11110100 | 0.84 | ELANE (0.67) | ELANEMAOATTRKDM4EHPGD | |
| SCHEMBL11104589 | 0.84 | KEAP1 (0.53) | ELANEMAOATTRKDM4EHPGD | |
| SCHEMBL16721016 | 0.84 | KCNA3 (0.56) | ELANEMAOATTRKDM4EHPGD | |
| SCHEMBL29019962 | 0.83 | KCNA3 (0.51) | ELANEMAOATTRKDM4EHPGD | |
| SCHEMBL23212346 | 0.83 | TTR (0.57) | ELANEMAOATTRKDM4EHPGD | |
| SCHEMBL8777904 | 0.83 | ADORA2A (0.60) | ELANEMAOATTRKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112955216-A | Releasable GLP-1 conjugates | 奎亚培格制药公司 | 2021-06-11 | — | — | CN | disclosed |
| CN-110545850-A | Releasable conjugates | QUIAPEG PHARMACEUTICALS AB | 2019-12-06 | — | — | CN | disclosed |