Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | EDNRB | P24530 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.48 |
| ▸ | FEN1 | P39748 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27806349 | 0.82 | KDM4E (0.54) | P2RX4KDM4EMAPK1HTTSMN1; SMN2 | |
| SCHEMBL27836563 | 0.78 | P2RX4 (0.61) | P2RX4KDM4EMAPK1HTTSMN1; SMN2 | |
| SCHEMBL14780906 | 0.77 | FEN1 (0.54) | P2RX4KDM4EMAPK1HTTSMN1; SMN2 | |
| SCHEMBL27806397 | 0.76 | P2RX4 (0.51) | P2RX4MAPK1SMN1; SMN2TP53LMNA | |
| SCHEMBL1061448 | 0.75 | L3MBTL1 (0.65) | P2RX4KDM4EMAPK1HTTSMN1; SMN2 | |
| SCHEMBL1440727 | 0.74 | EGLN1 (0.67) | P2RX4KDM4EMAPK1HTTSMN1; SMN2 | |
| SCHEMBL14160793 | 0.74 | P2RX4 (1.00) | P2RX4MAPK1SMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL18356958 | 0.73 | P2RX4 (0.82) | P2RX4KDM4EMAPK1HTTSMN1; SMN2 | |
| SCHEMBL30616070 | 0.73 | P2RX4 (0.82) | P2RX4KDM4EMAPK1HTTSMN1; SMN2 | |
| SCHEMBL24247594 | 0.73 | TP53 (0.65) | P2RX4MAPK1SMN1; SMN2HDAC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110115365-A | The adjusting that actinism receptor and relative ligand are carried out | 西诺米克斯公司 | 2019-08-13 | — | — | CN | disclosed |