SCHEMBL28313234

SCHEMBL28313234

Cc1ccc2c(c1N)C(=O)c1ccccc1C2=O.Nc1ccc2c(c1)C(=O)c1ccccc1C2=O

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.84
MAPK1 P28482 4/20 0.84
SMN1; SMN2 Q16637 4/20 0.84
NPC1 O15118 3/20 0.84
RAB9A P51151 3/20 0.84
CYP3A4 P08684 3/20 0.84
TSHR P16473 3/20 0.84
L3MBTL1 Q9Y468 2/20 0.84
CASP3 P42574 1/20 0.84
HBB P68871 1/20 0.84
SENP7 Q9BQF6 1/20 0.84
SENP6 Q9GZR1 1/20 0.84
TDP1 Q9NUW8 2/20 0.68
TP53 P04637 1/20 0.68
MEN1 O00255 4/20 0.61
POLB P06746 4/20 0.61
KMT2A Q03164 4/20 0.61
LMNA P02545 3/20 0.61
PTPRC P08575 2/20 0.61
NPSR1 Q6W5P4 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29558186 0.92 ALDH1A1 (1.00) ALDH1A1MAPK1SMN1; SMN2NPC1RAB9A
SCHEMBL591041 0.92 ALDH1A1 (1.00) ALDH1A1MAPK1SMN1; SMN2NPC1RAB9A
SCHEMBL28314829 0.87 ALDH1A1 (0.63) ALDH1A1MAPK1SMN1; SMN2NPC1RAB9A
SCHEMBL28509366 0.85 MAOA (0.80) ALDH1A1MAPK1SMN1; SMN2NPC1RAB9A
SCHEMBL10823870 0.82 ALDH1A1 (0.81) ALDH1A1MAPK1SMN1; SMN2NPC1RAB9A
Anthraquinone SCHEMBL23363689 0.82 NPC1 (1.00) ALDH1A1MAPK1SMN1; SMN2NPC1RAB9A
SCHEMBL31290097 0.82 NPC1 (1.00) ALDH1A1MAPK1SMN1; SMN2NPC1RAB9A
SCHEMBL40960 0.82 NPC1 (1.00) ALDH1A1MAPK1SMN1; SMN2NPC1RAB9A
SCHEMBL31615519 0.80 NPC1 (0.95) ALDH1A1MAPK1SMN1; SMN2NPC1RAB9A
SCHEMBL760965 0.80 NPC1 (0.95) ALDH1A1MAPK1SMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110092389-A A kind of tourmaline of surface grafting anthraquinone compounds, preparation method and application 厦门理工学院 2019-08-06 CN disclosed