Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 5/20 | 0.63 |
| ▸ | ESR1 | P03372 | 7/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.41 |
| ▸ | SHBG | P04278 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7932982 | 0.82 | HSD17B1 (0.64) | HSD17B1ESR1LMNAMAPK1ESR2 | |
| SCHEMBL2833904 | 0.81 | HSD17B1 (0.63) | HSD17B1ESR1LMNAMAPK1ESR2 | |
| SCHEMBL7056815 | 0.79 | ESR1 (0.71) | HSD17B1ESR1LMNAESR2CYP19A1 | |
| SCHEMBL7176305 | 0.79 | HSD17B1 (0.80) | HSD17B1ESR1LMNAMAPK1ESR2 | |
| SCHEMBL2833353 | 0.78 | ESR1 (0.58) | ESR1LMNAMAPK1ESR2CYP19A1 | |
| SCHEMBL12379610 | 0.78 | HSD17B1 (1.00) | HSD17B1ESR1LMNAMAPK1ESR2 | |
| SCHEMBL1977286 | 0.78 | HSD17B1 (1.00) | HSD17B1ESR1LMNAMAPK1ESR2 | |
| SCHEMBL2834941 | 0.77 | ESR1 (0.72) | HSD17B1ESR1LMNAMAPK1ESR2 | |
| SCHEMBL7921186 | 0.76 | HSD17B1 (0.76) | HSD17B1ESR1LMNAMAPK1ESR2 | |
| SCHEMBL12379651 | 0.76 | HSD17B1 (0.65) | HSD17B1ESR1LMNAMAPK1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242619-B1 | BEHAVIORAL OR PHYSIOLOGICAL RESPONSE, REDUCTION OF NEGATIVE AFFECT, MOOD, AND CHARACTER TRAITS; NASAL ADMINISTRATION OF VOMEROPHERINS OR PHEROMONES, NERVOUS SYSTEM DRUG MODE | PHERIN PHARMACEUTICALS, INC. | 2001-06-05 | — | — | US | claimed |
| US-20100111896-A1 | Items Containing A Human Pheromone Component | MARENBERG BARRY J | 2010-05-06 | — | — | US | disclosed |
| WO-2007062023-A2 | ITEMS CONTAINING A HUMAN PHEROMONE COMPONENT | BRAGINSKY PHILIP Y (US) | 2007-05-31 | — | — | WO | disclosed |