Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 15/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2834823 | 0.81 | ESR1 (0.60) | ESR1LMNAMAPK1SMN1; SMN2CYP19A1 | |
| SCHEMBL7056815 | 0.81 | ESR1 (0.71) | ESR1LMNASMN1; SMN2CYP19A1ESR2 | |
| SCHEMBL7060555 | 0.80 | ESR1 (0.58) | ESR1LMNAMAPK1SMN1; SMN2CYP19A1 | |
| SCHEMBL2838000 | 0.80 | ESR1 (0.58) | ESR1LMNAMAPK1SMN1; SMN2CYP19A1 | |
| SCHEMBL2831329 | 0.78 | HSD17B1 (0.63) | ESR1LMNAMAPK1CYP19A1ESR2 | |
| SCHEMBL2832728 | 0.78 | LMNA (0.65) | ESR1LMNAMAPK1SMN1; SMN2CYP19A1 | |
| SCHEMBL7174140 | 0.78 | LMNA (0.65) | ESR1LMNAMAPK1SMN1; SMN2CYP19A1 | |
| SCHEMBL2834240 | 0.78 | ESR1 (0.58) | ESR1LMNAMAPK1SMN1; SMN2CYP19A1 | |
| SCHEMBL2834461 | 0.77 | ESR1 (0.54) | ESR1LMNAMAPK1SMN1; SMN2CYP19A1 | |
| SCHEMBL2835430 | 0.76 | ESR1 (0.73) | ESR1LMNAMAPK1SMN1; SMN2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242619-B1 | BEHAVIORAL OR PHYSIOLOGICAL RESPONSE, REDUCTION OF NEGATIVE AFFECT, MOOD, AND CHARACTER TRAITS; NASAL ADMINISTRATION OF VOMEROPHERINS OR PHEROMONES, NERVOUS SYSTEM DRUG MODE | PHERIN PHARMACEUTICALS, INC. | 2001-06-05 | — | — | US | claimed |
| US-20100111896-A1 | Items Containing A Human Pheromone Component | MARENBERG BARRY J | 2010-05-06 | — | — | US | disclosed |