Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL932736 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL15525165 | 0.87 | — | — | |
| SCHEMBL2566272 | 0.84 | — | — | |
| Alcohol SCHEMBL10895476 | 0.77 | — | — | |
| Alcohol SCHEMBL646600 | 0.77 | — | — | |
| Trimethylammonium SCHEMBL7656962 | 0.75 | ALDH1A1 (0.31) | TSHRALDH1A1 | |
| Benzene SCHEMBL28041094 | 0.75 | LMNA (0.40) | TSHRALDH1A1 | |
| Isopropyl Alcohol SCHEMBL5605953 | 0.74 | TSHR (0.46) | TSHRALDH1A1TDP1 | |
| Alcohol SCHEMBL9085555 | 0.73 | — | — | |
| Isopropylamine SCHEMBL5724241 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110152506-A | A kind of filter medium and preparation method thereof selecting filtrating leukocytes | 广州达济医学科技有限公司 | 2019-08-23 | — | — | CN | disclosed |