Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 9/20 | 0.77 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.77 |
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.63 |
| ▸ | F2 | P00734 | 2/20 | 0.63 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.63 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.63 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.55 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.55 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.55 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.55 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.51 |
| ▸ | TNKS | O95271 | 1/20 | 0.51 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL754740 | 0.87 | PARP10 (1.00) | PARP10PARP3ST14F2PRSS1 | |
| SCHEMBL28313588 | 0.85 | PARP10 (0.73) | PARP10PARP3ST14F2PRSS1 | |
| SCHEMBL3693691 | 0.81 | PARP10 (0.64) | PARP10PARP3ST14F2PRSS1 | |
| SCHEMBL1718819 | 0.78 | PARP10 (0.71) | PARP10ST14F2PRSS1PRSS2 | |
| SCHEMBL3791103 | 0.77 | ST14 (1.00) | PARP10ST14F2PRSS1PRSS2 | |
| SCHEMBL1663469 | 0.77 | PARP10 (0.65) | PARP10PARP3ALDH1A1KMT2AKDM4E | |
| SCHEMBL5050902 | 0.77 | PARP10 (0.65) | PARP10PARP3ALDH1A1KMT2AKDM4E | |
| SCHEMBL28636841 | 0.77 | PARP10 (0.68) | PARP10PARP3ALDH1A1PARP15KMT2A | |
| SCHEMBL3793720 | 0.76 | PARP10 (0.81) | PARP10ST14F2PRSS1PRSS2 | |
| SCHEMBL3692809 | 0.76 | PARP10 (0.61) | PARP10PARP3ALDH1A1PARP15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696585-B1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5643931-A | ANTIDIABETIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0696585-A1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |